THE MANHATTAN PRODUCT OF DIGRAPHS

The Manhattan product of digraphs

We study the main properties of a new product of bipartite digraphs which we call Manhattan product.This product allows us to understand the subjacent product Embedding Mathematics in Socio-Scientific Games: The Mathematical in Grappling with Wicked Problems in the Manhattan street networks and can be used to built other networks with similar good

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A multiparameter liquid biopsy approach allows to track melanoma dynamics and identify early treatment resistance

Abstract Melanoma heterogeneity is a hurdle in metastatic disease management.Although the advent of targeted therapy has significantly improved patient outcomes, the occurrence of resistance makes monitoring of the tumor genetic landscape mandatory.Liquid biopsy could represent an important biomarker for the real-time tracing of disease evolution.T

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